Treatment Comparison
Available Supply Options
& Microdose vs Standard GLP-1
Understand the key differences between your provider-guided GLP-1 options.
Your prescribing provider makes the final decision based on your clinical evaluation.
RECEPTOR PATHWAYS
Semaglutide vs Tirzepatide
Both are provider-guided compounded GLP-1 options.
The key difference is how many metabolic pathways they act on.
GLP-1 receptor agonist
Semaglutide
Mimics the body’s natural GLP-1 hormone to support appetite regulation and metabolic health.
From $218.99
Dual GIP & GLP-1 receptor agonist
Tirzepatide
Acts on two metabolic pathways (GIP and GLP-1) to support appetite regulation and glucose metabolism.
From $262.99
Feature
Semaglutide
Tirzepatide
Receptor pathway
GLP-1 only
GIP + GLP-1 (dual)
Mechanism
Mimics natural GLP-1 hormone
Activates two metabolic pathways
Supply options
4-Week & 12-Week
4-Week & 12-Week
Starting price (4-week)
$218.99
$262.99
Pharmacy
Nova Specialty Pharmacy
Nova Specialty Pharmacy
Excluded states
AL, CA, MS
AL, CA, MS
Prescription guaranteed?
No — provider decides
No — provider decides
DOSE APPROACH
Microdose vs Standard GLP-1
Microdosing is an individualized lower-dose approach — not a different medication. It uses the same active ingredient
at a provider-selected lower dose based on your health history and tolerability.
Standard Dose
Follows an established titration schedule with 4-week and 12-week supply options. The provider selects the appropriate dose from the listed options based on your clinical evaluation.
Microdose
An individualized lower-dose approach selected with a provider based on your health history, treatment response, and tolerability. Available as a 4-week supply only. Evidence for microdosing is limited, and lower doses can still cause side effects.
Feature
Standard
Microdose
Dose approach
Standard titration schedule
Individualized lower dose
Receptor pathway
Same as standard (GLP-1 or dual)
Same pathway, lower dose
Supply
4-Week & 12-Week
4-Week only
Who decides the dose
Prescribing provider
Prescribing provider
Evidence base
Established titration protocols
Limited evidence; side effects still possible
Weight loss guaranteed?
No — results vary
No — results vary
FREQUENTLY ASKED QUESTIONS
GLP-1 comparison questions
Semaglutide is a GLP-1 receptor agonist, acting on a single metabolic pathway. Tirzepatide is a dual GIP and GLP-1 receptor agonist that acts on two metabolic pathways. Your provider determines which is appropriate based on your clinical evaluation, health history, and treatment goals.
Microdosing is an individualized lower-dose approach selected with a provider based on health history, treatment response, and tolerability. Standard options follow established titration schedules. Evidence for microdosing is limited, and lower doses can still cause side effects. Weight loss may occur but is not guaranteed.
No. The appropriate medication is determined by a licensed provider following your medical evaluation. You can express preferences, but the clinical decision rests with your prescriber based on safety, eligibility, and individual health factors.
Both Semaglutide and Tirzepatide offer 4-week and 12-week supply options, but pricing differs. Semaglutide starts at $218.99 for a 4-week supply; Tirzepatide starts at $262.99. Microdosing options are 4-week only. See each product page for full dose and pricing details.
These are compounded medications prepared by licensed compounding pharmacies pursuant to individualized prescriptions. Compounded medications are not FDA-approved or evaluated by the FDA for safety, effectiveness, or quality. Prescriptions are not guaranteed.
Important to know
- Compounded medications are not FDA-approved.
- No specific outcome, including weight loss, is guaranteed.
- Your provider chooses the medication and dose based on your evaluation.
- Both options include discreet 3 to 5 day home delivery.
Not sure which is right for you?
That’s exactly what your provider helps determine during your evaluation.